# Tranexamic Acid (TXA)

If a casualty is anticipated to need significant blood transfusion (for example: presents with hemorrhagic shock, one or more major amputations, penetrating torso trauma, or evidence of severe bleeding):

- Administer 1 gram of Tranexamic Acid in 100 mL Normal Saline or Lactated Ringers as soon as possible but NOT later than 3 hours after injury. When given, the TXA should be administered over 10 minutes by IV infusion.

- Begin second infusion of 1 gm TXA after Hextend or other fluid treatment.