The Efficacy and Safety of Tranexamic Acid Treatment in Orthopaedic Trauma Surgery

Cody R Perskin, Connor P Littlefield, Charles Wang, Uchenna Umeh, Kenneth A Egol

JBJS Rev. 2021 Jul 16;9(7)

 

Abstract

»: Tranexamic acid (TXA) is a drug used to control hemorrhage by preventing the breakdown of fibrin.

»: TXA is a cost-effective treatment for trauma patients across a variety of economic settings.

»: Concerns of TXA causing thromboembolic events (TEEs) in orthopaedic trauma patients are not supported by evidence.

»: TXA has been shown to reduce blood loss in hip fracture surgery.