Several hemorrhage control guidelines recommend that any obvious bleeding in a compressible area should be treated with direct digital pressure first, as direct pressure can effectively control bleeding and be used as a temporary measure until a tourniquet or dressing can be applied. Although it is difficult to maintain direct pressure to control significant bleeding when working alone or while moving a casualty, it should be attempted while gathering and preparing equipment for more definitive treatment. When possible, ask other responders to assist in order to avoid releasing pressure while preparing for a more definitive hemorrhage control measure.

The exact site for applying direct pressure requires adequate exposure and assessment of the bleeding source. In cases of severe hemorrhage, it may be very difficult to determine the exact source of bleeding without exposing and exploring the wound carefully. And, in some cases, the source may not be easily identified.