Ann Emerg Med. 2018 Aug;72(2):133-134

# Is low-dose ketamine an effective alternative to opioids for the treatment of acute pain in the emergency department?

Gottlieb M, Ryan K, Binkley C

According to limited evidence, low-dose ketamine and morphine appear to provide similar levels of pain relief at 30 minutes; however, low-dose ketamine is associated with a higher rate of self-limited neuropsychological adverse events.