Complete Aortic Occlusion:

Zone 1 REBOA – 60 minutes maximum, optimally < 30 minutes.

Zone 3 REBOA – 60 minutes.

Preclinical research has shown a Zone 1 complete aortic occlusion time of 60 minutes or more results in significant metabolic derangement and organ damage that may negate any benefits obtained by its assistance with hemorrhage control.54,74 In comparison, complete occlusion time of 30 minutes or less significantly improved outcomes without evidence of severe physiologic costs.