Complete Aortic Occlusion:

Zone 1 REBOA – 60 minutes maximum, optimally < 30 minutes.

Zone 3 REBOA – 60 minutes.

Preclinical research has shown a Zone 1 complete aortic occlusion time of 60 minutes or more results in significant metabolic derangement and organ damage that may negate any benefits obtained by its assistance with hemorrhage control.^54,74 In comparison, complete occlusion time of 30 minutes or less significantly improved outcomes without evidence of severe physiologic costs.