Transfusion therapy is indicated for MWDs experiencing any condition (trauma, neoplasia, other) that results in acute blood loss or clinical anemia, or that significantly increases their bleeding risk (e.g., severe thrombocytopenia, Acute Traumatic Coagulopathy/Trauma-Induced Coagulopathy,8 other). Consider transfusion therapy as a first-line intervention for perioperative hemodynamic optimization in MWDs that have suffered major trauma. These guidelines focus on transfusion for MWDs injured as the result of trauma in a forward deployed environment and will focus only on canine blood products expected to be found in theater – specifically canine Whole Blood, Fresh Frozen Plasma and Freeze Dried Plasma. These guidelines should therefore not be used for all conditions.