While various necessary military occupations put service members at increased risk for drowning, particularly those serving in the Navy and Marine Corps, this risk is mitigated through methodical training and operational risk management processes. However, drowning events in combat and operational environments can occur and are highly influenced by the tactical environment. In civilians, drowning is thought to be preventable in over 90% of cases.1-2 As a result of the significant human, social, and economic tolls of drowning, the World Health Assembly adopted their first resolution regarding drowning prevention in 2023.3 The purpose of this clinical practice guideline provides an overview of drowning and associated conditions based on the best available current medical evidence. It should be used as a standardized framework to guide first responders, prehospital emergency medical service personnel, and medical department personnel in evaluating, diagnosing, and managing common in-water emergencies. Caregivers supporting operations with an increased risk of drowning should review this CPG with the entire medical team including first responders.