Although TXA is very stable throughout a range of temperatures for several days (preferably, 59°-86° F), there are no studies to support storage outside of the original packaging (for example, in a pre-drawn syringe). Avoid exposure to extreme environments during missions and store in a more controlled environment between missions.

Remember, administer 2 grams of TXA using a slow IV or IO push as soon as possible, if it is indicated.

### CONTRAINDICATIONS

Hypersensitivity to TXA, subarachnoid hemorrhage, active intravascular clotting, considered relatively safe in pregnancy, if clinically indicated

### POTENTIAL SIDE EFFECTS

Blurred vision or impaired color vision, nausea, vomiting, diarrhea (temporary)

### DRUG INTERACTIONS

Factor IX complex concentrates or anti-inhibitor coagulant concentrates (risk of thrombosis may be increased)

### ONSET/PEAK/DURATION

30 sec - 5 min / 30 min - 2 hr / 24 hr

### TACTICAL CONSIDERATIONS

Administer as soon as possible but not later than 3 hours after injury.

Studies have confirmed that TXA can be safely administered in the same IV line as blood, crystalloid fluids, and Hextend®.