Although TXA is very stable throughout a range of temperatures for several days (preferably, 59°-86° F), there are no studies to support storage outside of the original packaging (for example, in a pre-drawn syringe). Avoid exposure to extreme environments during missions and store in a more controlled environment between missions.
Remember, administer 2 grams of TXA using a slow IV or IO push as soon as possible, if it is indicated.
Hypersensitivity to TXA, subarachnoid hemorrhage, active intravascular clotting, considered relatively safe in pregnancy, if clinically indicated
Blurred vision or impaired color vision, nausea, vomiting, diarrhea (temporary)
Factor IX complex concentrates or anti-inhibitor coagulant concentrates (risk of thrombosis may be increased)
30 sec - 5 min / 30 min - 2 hr / 24 hr
Administer as soon as possible but not later than 3 hours after injury.
Studies have confirmed that TXA can be safely administered in the same IV line as blood, crystalloid fluids, and Hextend®.