Even with the active hemostatic agents in hemostatic dressings, wound packing and direct pressure are required to control bleeding.

Whenever possible, identify the exact source of bleeding and apply direct pressure as a temporary measure while preparing hemostatic gauze for placement. Pack the wound maximizing contact between the hemostatic gauze and the active site of bleeding. Maintain constant direct pressure at the source of bleeding while packing the wound.  After the wound has been packed, hold direct pressure over the gauze on the wound for at least 3 minutes. This is necessary even with the active hemostatic agent in the gauze.

When packing a large wound, more than one hemostatic gauze and/or additional gauze may be needed. Carefully observe the wound to determine if bleeding has been effectively controlled. Once bleeding has been controlled, apply a pressure bandage.