Tranexamic acid for acute traumatic hemorrhage in emergency medicine: why not, but…

Matthieu Heidet

Eur J Emerg Med 2020 Apr;27(2):85-86

Current guidelines broadly recommend using TXA in severely injured patients. While TXA appears to be cheap, easy, well tolerated and efficient, clinicians should remain aware of the limitations of the available results, remind that TXA should be used within precise indications, in accordance with broader key practices in trauma patients, and look forward to answering pending interrogations. Clinicians should adopt a cautious approach in order to limit their use of TXA to the most severe patients and stay aware that many gaps remain unanswered to date.

Current strategy of ‘rapid TXA for all’ may improperly lead to overexpose patients who would not benefit from this practice.