REFERENCES

   

  1. Geerts WH, Code KJ, Jay RM, et al: A prospective study of venous thromboembolism after major trauma. N Engl J Med 1994;331(24):1601-1606.
  2. Sevitt S, Gallagher N. Venous thrombosis and pulmonary embolism. A clinico-pathological study in injured and burned patients. Br J Surg 1961;48:475-489.
  3. Godat LN Kobayashi L, Chang DC et al. Can we ever stop worrying about venous thromboembolism after trauma? J Trauma 2015;78(3):475-480.
  4. Differding JA, Underwood SJ, Van PY, et al. Trauma induces a hypercoagulable state that is resistant to hypothermia as measured by thromboelastogram. Am J Surg 2011;201(5):587-591.
  5. Gearhart MM, Luchette FA, Proctor MC, et al. The risk assessment profile score identifies trauma patients at risk for deep venous thrombosis. Surgery 2000;128(4):631-637.
  6. Spinella PC, Carroll CL, Staff I, et al. Duration of red blood cell storage is associated increased incidence of deep venous thrombosis and in hospital mortality in patients with traumatic injuries. Critical Care 2009;13(5):R151.
  7. Hutchinson TN, Krueger CA, Berry, JS, et al. Venous thromboembolism during combat operations: a 10-y review. J Surg Res 2014;187(2):625-630.
  8. Knudson MM: Thromboembolism after trauma: an analysis of 1602 episodes from the American College of Surgeons National Trauma Data Bank.  Ann Surg 2004: 490-496.
  9. Zander AL, Olson EJ, Van Gent JM, et al. Does resuscitation with plasma increase the risk of venous thromboembolism? J Trauma 2015;78(1):39-43.
  10. Hanson SJ, Punzalan RC, Greenup RA, et al. Incidence and risk factors for venous thromboembolism in critically ill children after trauma. J Trauma 2010;68(1):52-56.
  11. Scurr JH, Machin SJ, Bailey-King S, et al. Frequency and prevention of symptom-less deep venous thrombosis in long haul flights: a randomized trial, Lancet 2001; 357:1485-1489.
  12. Holley AB, Petteys S, Mitchell JD, et al. Thromboprophylaxis and VTE rates in soldiers wounded in Operation Enduring Freedom and Operation Iraqi Freedom. Chest 2013;144(3):966-973.
  13. Rogers FB, Cipolle MD, Velmahos G, et al. Practice management guidelines for the prevention of venous thromboembolism in trauma patients: the EAST practice management guidelines work group. J Trauma 2002;53(1):142-164.
  14. Guyatt GH, Akl EA, Crowther M, et al. Antithrombotic therapy and prevention of thrombosis, 9th edition: American College of Chest Physicians evidence based clinical practice guidelines. Chest 2012;141(2):7S-47S.
  15. Rappold JF, Sheppard FR, Carmichael II SP, et al. Venous thromboembolism prophylaxis in the trauma intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document Trauma Surgery & Acute Care Open 2021;6:e000643.
  16. Ley, EJ, Brown CVR, Moore EE, et al. Updated guidelines to reduce venous thromboembolism in trauma patients: A Western Trauma Association critical decisions algorithm, Journal of Trauma and Acute Care Surgery: Nov 2020. 89(5): 971-981.
  17. Mahajerin A, Petty JK, Hanson, SJ, et al. MHS Prophylaxis against venous thromboembolism in pediatric trauma, Journal of Trauma and Acute Care Surgery: Mar 2017; 82(3): 627-636
  18. Jacobs BN, Cain-Nielsen AH, Jakubus JL, et al. Unfractionated heparin versus low-molecular-weight heparin for venous thromboembolism prophylaxis in trauma. J Trauma Acute Care Surg. 2017;83(1):151–158.
  19. Walker CK, Sandmann EA, Horyna TJ, Gales MA. Increased enoxaparin dosing for venous thromboembolism prophylaxis in general trauma patients. Ann Pharmacother. 2017;51(4):323–331.
  20. Bickford A, Majercik S, Bledsoe J, et al. Weight-based enoxaparin dosing for venous thromboembolism prophylaxis in the obese trauma patient. Am J Surg. 2013;206(6):847–851; discussion 851-2.
  21. Nunez JM, Becher RD, Rebo GJ, Farrah JP, Borgerding EM, Stirparo JJ, Lauer C, Kilgo P, Miller PR. Prospective evaluation of weight-based prophylactic enoxaparin dosing in critically ill trauma patients: adequacy of AntiXa levels is improved. Am Surg. 2015;81(6):605–609.
  22. Berndtson AE, Costantini TW, Lane J, Box K, Coimbra R. If some is good, more is better: an enoxaparin dosing strategy to improve pharmacologic venous thromboembolism prophylaxis. J Trauma Acute Care Surg. 2016;81(6):1095–1100.
  23. Rodier SG, Bukur M, Moore S, et al. Weight-based enoxaparin with anti-factor Xa assay-based dose adjustment for venous thromboembolic event prophylaxis in adult trauma patients results in improved prophylactic range targeting. Eur J Trauma Emerg Surg. 2019.
  24. Gould MK, Garcia DA, Wren SM, et al. Prevention of VTE in nonorthopedic surgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(S2):e227S–e277S.
  25. Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S, Crowther M. Treatment and prevention of heparin-induced thrombocytopenia: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(Suppl 2):e495S–e530S.
  26. Warkentin TE, Levine MN, Hirsh J, Horsewood P, Roberts RS, Gent M, Kelton JG. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med. 1995;332(20):1330–1335.
  27. Berry C, Tcherniantchouk O, Ley EJ, et al. Overdiagnosis of heparin-induced thrombocytopenia in surgical ICU patients. J Am Coll Surg. 2011;213(1):10–17.
  28. Harada MY, Hoang DM, Zaw AA, et al. Overtreatment of heparin-induced thrombocytopenia in the surgical ICU. Crit Care Med. 2017;45(1):28–34.
  29. Geerts WH, Jay RM, Code KJ, et al. A comparison of low-dose heparin with low-molecular weight heparin as prophylaxis against venous thromboembolism after major trauma. New England Journal of Medicine 1996;335(10):701-707.
  30. Whitworth JM, Schneider KE, Frederick PJ, et al. Double prophylaxis for deep venous thrombosis in patients with gynecologic oncology who are undergoing laparotomy: does preoperative anticoagulation matter? International Journal of Gynecologic Cancer 2011;21(6):1131-1134.
  31. Selby LV, Sovel M, Sjoberg DD, et al. Preoperative chemoprophylaxis is safe in major oncology operations and effective at preventing venous thromboembolism. J Am Coll Surg. 2016;222(2):129–137.
  32. Hull RD, Pineo GF, Stein PD, et al. Timing of initial administration of low-molecular-weight heparin prophylaxis against deep vein thrombosis in patients following elective hip arthroplasty: a systematic review. Arch Intern Med. 2001;161(16):1952–1960.
  33. Louis SG, Sato M, Geraci T, et al. Correlation of missed doses of enoxaparin with increased incidence of deep vein thrombosis in trauma and general surgery patients. JAMA Surg. 2014;149(4):365–370.
  34. Meyer RM, Larkin MB, Szuflita NS, et al. Early venous thromboembolism chemoprophylaxis in combat-related penetrating brain injury. J Neurosurg. 2017;126(4):1047–1055.
  35. Pastorek R, Cripps M, Bernstein I, et al. The Parkland Protocol’s modified Berne-Norwood criteria predict two-tiers of risk for traumatic brain injury progression. J of Neurotrauma 2014; 31: 1737-1743.
  36. Phelan HA, Eastman AL, Madden CJ, et al. TBI risk stratification at presentation: A prospective study of the incidence and timing of radiographic worsening in the Parkland Protocol. Journal Trauma Acute Care Surgery 2012; 73: S122-S127.
  37. Salottolo K, Offner P, Levy AS, Mains CW, Slone DS, Bar-Or D. Interrupted pharmocologic thromboprophylaxis increases venous thromboembolism in traumatic brain injury. J Trauma. 2011;70(1):19–24; discussion 25-6.
  38. Kim DY, Kobayashi L, Chang D, Fortlage D, Coimbra R. Early pharmacological venous thromboembolism prophylaxis is safe after operative fixation of traumatic spine fractures. Spine. 2015;40(5):299–304.
  39. Christie S, Thibault-Halman G, Casha S. Acute pharmacological DVT prophylaxis after spinal cord injury. J Neurotrauma. 2011;28(8):1509–1514.
  40. Coleman JR, Kay AB, Moore EE, et al. It's sooner than you think: blunt solid organ injury patients are already hypercoagulable upon hospital admission — results of a bi-institutional, prospective study. Am J Surg. 2019;218(6):1065–1073.
  41. Sumislawski JJ, Kornblith LZ, Conroy AS, Callcut RA, Cohen MJ. Dynamic coagulability after injury: is delaying venous thromboembolism chemoprophylaxis worth the wait? J Trauma Acute Care Surg. 2018;85(5):907–914.
  42. Schellenberg M, Inaba K, Biswas S, et al. When is it safe to start VTE prophylaxis after blunt solid organ injury? A prospective study from a level I trauma center. World J Surg. 2019;43(11):2797–2803.
  43. Horlocker TT, Vandermeuelen E, Kopp SL, Gogarten W, Leffert LR, Benzon HT. Regional Anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine evidence-based guidelines (fourth edition). Reg Anesth Pain Med. 2018;43(3):263–309.
  44. Gogarten W, Vandermeulen E, Van Aken H, et al. Regional anaesthesia and antithrombotic agents: recommendations of the European Society of Anaesthesiology. Eur J Anaesthesiol. 2010;27(12):999–1015.
  45. Stone AB, Grant MC, Lau BD, et al. Thoracic epidural anesthesia and prophylactic three times daily unfractionated heparin within an enhanced recovery after surgery pathway for colorectal surgery. Reg Anesth Pain Med. 2017;42(2):197–203.
  46. Vella MA, Dumas RP, Chreiman K, et al. Epidural catheters are associated with an increased risk of venous thromboembolism in trauma. J Thromb Thrombolysis. 2020;49:420–425.
  47. Zaw AA, Murry J, Hoang D, et al. Epidural analgesia after rib fractures. Am Surg. 2015;81(10):950–954.
  48. Gage A, Rivara F, Wang J, Jurkovich GJ, Arbabi S. The effect of epidural placement in patients after blunt thoracic trauma. J Trauma Acute Care Surg. 2014;76(1):39–45; discussion 45-6.
  49. Duhl AJ, Paidas MJ, Ural SH, et al; Pregnancy and Thrombosis Working Group. Antithrombotic therapy and pregnancy: consensus report and recommendations for prevention and treatment of venous thromboembolism and adverse pregnancy outcomes. Am J Obstet Gynecol. 2007;197(5):457.e1–457.e21.
  50. Eubanks AA, Deering SH, Thiel LM. Risk assessment and treatment guide for obstetric thromboprophylaxis: comprehensive review of current guidelines. Am J Perinatol. 2019;36(2):130–135.
  51. Lamont MC, McDermott C, Thomson AJ, et al. United Kingdom recommendations for obstetric venous thromboembolism prophylaxis: evidence and rationale. Semin Perinatol. 2019;43(4):222–228.
  52. Allen CJ, Murray CR, Meizoso JP, Ginzburg E, Schulman CI, Lineen EB, Namias N, Proctor KG. Surveillance and early management of deep vein thrombosis decreases rate of pulmonary embolism in high-risk trauma patients. J Am Coll Surg. 2016;222(1):65–72.
  53. Rostas JW, Manley J, Gonzalez RP, et al. The safety of low molecular weight heparin after blunt liver and spleen injuries. Am J Surg 2015 Jul;210(1):31-34.
  54. Joseph B, Pandit V, Harrison C, et al. Early thromboembolic prophylaxis in patients with blunt solid abdominal organ injuries undergoing nonoperative management: is it safe? Am J Surg 2015;209(1):194-198.